About Dr Sebastian Zeki

Dr. Zeki qualified in medicine from Cambridge University and University College London in 2001.

He undertook his postgraduate medical training in London during which time he also completed a PhD on the genomics of oesophageal cancer, under Professor Sir Nicholas Wright and Dr Stuart Macdonald. This was recognised and presented at national and international meetings and recognised with several prizes from British, European and American Gastroenterological Societies.

He subsequently completed further clinical training alongside postdoctoral research at Addenbrooke’s Hospital and the Medical Research Council Hutchison laboratory, Cambridge and Jikei University Hospital, Tokyo.

“I have known Dr. Zeki for many years. He is one of the most knowledgeable, thoughtful, kind and skilled physicians in his field. Dr Zeki is an expert in Gastroenterology and Endoscopy always pushing the boundaries of innovation and applying the latest research and endoscopy techniques in his practice, therefore his patients are guaranteed to get the best quality care and attention. Would highly recommend him and he would be my first choice doctor to see if I ever get ill!”

– Dr Sarmed Sami on Doctify

A Private Gastroenterologist for patients in Central London

Dr Sebastian Zeki is a gastroenterologist at St Thomas’ Hospital in London one of the country’s leading tertiary referral centres. He is also a senior clinical lecturer at Kings College University and Barts cancer institute.

At the heart of this work and projects, is you, the patient.


  • Endoscopic therapy
  • Oesophageal and stomach cancers/Barrett’s oesophagus
  • Oesophageal physiology
  • Heartburn; chest pain; indigestion; bloating; spasm; dyspepsia; irritable bowel syndrome; swallowing disorders; hoarse voice; chronic cough and throat clearing
  • Eosinophilic oesophagitis
  • High quality endoscopy
  • Machine learning/R/Natural language programming
  • Genomics


  • Honorary Senior Clinical Lecturer, King’s College London – October 2019 – Present
  • Co-head of the Gastroenterology Data Sciences Institute, Guy’s & St Thomas’ NHS Trust – January 2017 – Present
  • Honorary Senior Clinical Lecturer, Bart’s Cancer Institute – January 2017 – Present
  • Consultant Gastroenterologist, Guy’s & St Thomas’ NHS Trust – April 2015 – Present
  • Clinical Lecturer, Cambridge University: MRC Hutchison, June 2013 – April 2015
  • PhD student, Queen Mary University of London – January 2010 – June 2013
  • Gastroenterology registrar, North West Thames Training Rotation, June 2006 – January 2016
  • Postgraduate internal medicine training – June 2001 – June 2006


  • Acid reflux and reflux related conditions
  • Bloating, swollen abdomen, vomiting and feeling gassy
  • Eosinophilic oesophagitis and food allergies
  • Detection, surveillance and resection of early GI cancers and pre-cancers
  • Swallowing problems


  • PhD – Genomics of Barret’s related malignancy, 2013, University of London
  • Member of the Royal College of Physician, 2006
  • MSc Health Informatics, 2003, City University
  • MBBS MBChir Medicine, 2001, University College London
  • MA in experimental psychology, 1998, Cambridge University



A basic tutorial on data science methods as applied to gastroenterological data. This will explain the basic principles of natural language processing as applied to endoscopy and pathological text to allow information to be extracted in an automated way.

Improving lesion recognition using text 

Health Foundation grant to use endoscopic and pathological free text merge with images to improve lesion recognition in trainees by automating individual metrics.


A package written in R to automate extraction of endoscopic metrics from free text reports. R is a functional programming language and one of the most commonly used. Here it is applied to endoscopic and pathological natural language text. The open source package can execute on any body of text. The package comes with a well developed tutorial and plenty of examples.

MiFlo – a single page patient flow manager to help virtual consultations

A Shiny app that visually represents a patients timeline of investigations with summarised results as well as appointments. The excess of information that electronic data has brought with it means that there is now a desperate need to show only data that is needed to make a decision about a patient rather than to drown a clinician in a lot of unnecessary information. MiFlo provides this filter. It was initially developed for gastroenterology but is equally configurable to any clinical environment.

Gastroenterology book

A visual training manual for Gastroenterologists with automated MCQ’s. Gastroenterology training covers a huge number of subjects. The gastroenterology training book was the first online attempt to provide a comprehensive training book where each subject is treated as a single, visually represented page. Each page can automatically generate MCQ’s from the page so that there are an unlimited number of MCQs on the site. If you log in (which is free) you can get your performance on the MCQ’s as well as your reading metrics so you can discover your knowledge gaps.

Recent & Upcoming Talks

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Get in touch with us however you prefer

Dr Zeki offers consultations in Central London and looks forward to hearing from you.