About Dr Sebastian Zeki
Dr Sebastian Zeki is a Consultant Gastroenterologist seeing private patients at HCA UK at The Shard and London Bridge Hospital, with particular expertise in acid reflux, Barrett's oesophagus, swallowing difficulties, eosinophilic oesophagitis and early cancer detection and treatment, as well as general gastroenterological conditions.
He is one of a small number of London consultants personally delivering advanced reflux diagnostics — BRAVO wireless pH monitoring, pH‑impedance studies and high‑resolution oesophageal manometry — meaning patients with persistent or unexplained reflux symptoms can be investigated and treated within a single pathway. He performs gastroscopy and colonoscopy in JAG‑accredited endoscopy units, including endoscopic diagnosis and resection of early cancers.
Training and appointments
Dr Zeki qualified from Cambridge University and University College London in 2001 and completed a PhD in the genomics of oesophageal cancer, with postdoctoral research at Addenbrooke's Hospital, the MRC Cancer Unit in Cambridge, and Jikei University Hospital, Tokyo. He was appointed consultant at Guy's and St Thomas' NHS Foundation Trust in 2015, where he co‑leads the Gastroenterology Data Science Institute, and is an honorary senior clinical lecturer at King's College London.
Special interests
- Acid reflux and heartburn, including reflux that has not responded to medication
- Barrett's oesophagus — surveillance and endoscopic therapy
- Swallowing difficulties, oesophageal spasm and motility disorders
- Eosinophilic oesophagitis and food allergy affecting the gut
- Chronic cough, throat clearing, hoarse voice and chest pain related to reflux
- Indigestion, dyspepsia, bloating and irritable bowel syndrome
- Endoscopic cancer diagnosis and resection; gastric cancer screening
Research and recognition
Dr Zeki's research spans upper gastrointestinal cancer and its precursors, oesophageal physiology, and the use of data science to improve endoscopy quality. His work has been recognised with awards from the British, European and American gastroenterological societies, and he has published in leading journals including the American Journal of Gastroenterology and npj Digital Medicine.
How Dr Zeki works
Every consultation is unhurried and clear. The aim is that you leave understanding your symptoms, your options and the plan — and that problems are resolved promptly. Where testing is needed it is arranged quickly, usually at London Bridge Hospital, and results are explained in person or by video consultation, whichever suits you.